Internet Information Services (IIS) 6.x had limited support for IPv6, but IIS7.x and later has good support for IPv6 features, from creating site bindings to logging to security features like IP Restriction. IIS7.x and later versions also work well under Server 2008 and later. Using IPv6 can be as simple as starting IIS after installing it on your system. IPv6 support with earlier operating systems is problematic.

A basic IIS6.x configuration example would be

Open IIS Manager (inetmgr)
Select the site you wish to enable IPv6 on
From the Action pane choose “Bindings…”
type = http (for a basic web server)
IP address = ipv6 address (or use the drop down list)
port = 80
host name = the name you want the server to respond to

Click Ok

Configuring IIS7.x and later changed. The IIS6.x metabase was replaced by an XML-based procedure. Microsoft provides a website for general IIS support: For more detailed information about using IIS7.0 with IPv6 visit Nazim's IIS Security Blog. Another IIS7.0 write-up is available on the SoftLayer KnowledgeBase. Remember to install an updated file transfer protocol (FTP) publishing service. It was released after IIS7.0. This step is mentioned by both articles. Articles on the Microsoft website for IIS configuration are available: IIS7.5, IIS8.0, and IIS8.5. (IIS10.0 configuration is just like IIS8.5 except IIS10.0 is only available on Windows 10/11.)

Limited information about IIS6.x support for IPv6 running under Server 2003 is available in this article and security guide.

For all versions of IIS, complete the 8 steps described in this Get Your Site Ready for IPv6 article for the host computer your IIS web server is installed on.

Note: If you want both IIS and an instance of the Microsoft .NET Framework on the same computer in Windows Server 2003 (also applies to 2008 and later), it is better to install IIS first. (If the Microsoft .NET Framework was installed before installing IIS, see this article for a possible solution).